MELD & MELD-Na Liver Disease Severity Score Reference Calculator

Compute MELD(i) = 9.57·ln(Cr) + 3.78·ln(Bili) + 11.2·ln(INR) + 6.43 and Na adjustment.

MELD-Na Composite Score
22 points
Baseline MELD(i) Score (Pre-Sodium) 18.81 pts
Hyponatremia Point Adjustment 3.5 pts
Clamped Serum Sodium Used 132 mEq/L
Inputs
mg/dL
Serum Creatinine in mg/dL (clamped 1.0 to 4.0 per UNOS rule).
mg/dL
Total Serum Bilirubin in mg/dL (minimum 1.0).
INR
International Normalized Ratio (INR, minimum 1.0).
mEq/L
Serum Sodium in mEq/L (clamped 125 to 137 mEq/L).
Results & Graph
MELD-Na Composite Score
22 points
Baseline MELD(i) Score (Pre-Sodium)
18.81 pts
Hyponatremia Point Adjustment
3.5 pts
Clamped Serum Sodium Used
132 mEq/L

MELD-Na Composite Score

Graph 1 • Serum Creatinine Mg Dl Sensitivity Recalculates the domain equation across 50% to 150% of the primary input while holding other parameters constant.
0 points 14.0 points 28.1 points 50%: 20 points 20 50% 75%: 20 points 20 75% 100%: 22 points 22 100% 125%: 24 points 24 125% 150%: 26 points 26 150%
Graph 2 • Primary & Supporting Metric Comparison Compares the primary output alongside supporting domain benchmarks.
MELD-Na Composite Score 22 points Baseline MELD(i) Score (Pre-Sodium) 18.81 pts Hyponatremia Point Adjustment 3.5 pts Clamped Serum Sodium Used 132 mEq/L
Graph 3 • Exact Output Table & Units Displays each calculated output in its exact domain unit.
MELD-Na Composite Score22 pointsBaseline MELD(i) Score (Pre-Sodium)18.81 ptsHyponatremia Point Adjustment3.5 ptsClamped Serum Sodium Used132 mEq/L
Summary: Baseline MELD(i) is 18.8 and sodium-adjusted MELD-Na is 22 points (at Na = 132 mEq/L).
Summary: Baseline MELD(i) is 18.8 and sodium-adjusted MELD-Na is 22 points (at Na = 132 mEq/L).
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Formula & Mathematical Methodology: MELD-Na Liver Score Reference Equation

MELD(i) = 9.57·ln(Cr) + 3.78·ln(Bili) + 11.20·ln(INR) + 6.43
MELD-Na adjusts for Na 125–137 mEq/L
MELD(i) = 9.57·ln(Cr) + 3.78·ln(Bili) + 11.20·ln(INR) + 6.43; MELD-Na adjusts for Na 125–137 mEq/L
  • serumCreatinineMgDl: Serum Creatinine Mg Dl (mg/dL)
  • totalBilirubinMgDl: Total Bilirubin Mg Dl (mg/dL)
  • inrCoagulation: Inr Coagulation (INR)
  • serumSodiumMeqL: Serum Sodium Meq L (mEq/L)

Rounding: Laboratory and clinical equations retain full floating-point precision and round displayed results to 2 decimal places.

Worked Example: Reference Calculation: MELD-Na Liver Score

Compute MELD(i) = 9.57·ln(Cr) + 3.78·ln(Bili) + 11.2·ln(INR) + 6.43 and Na adjustment.

  1. Enter the reagent concentrations, assay readings, or clinical laboratory parameters.
  2. Compute the standard formula: MELD(i) = 9.57·ln(Cr) + 3.78·ln(Bili) + 11.20·ln(INR) + 6.43; MELD-Na adjusts for Na 125–137 mEq/L.
  3. Review the primary result, supporting reference intervals, and 3 SVG visualizations.
Result: Evaluates MELD-Na Liver Score via MELD(i) = 9.57·ln(Cr) + 3.78·ln(Bili) + 11.20·ln(INR) + 6.43; MELD-Na adjusts for Na 125–137 mEq/L.

Frequently Asked Questions

What formula is used by the MELD & MELD-Na Liver Disease Severity Score Reference Calculator?

It computes MELD(i) = 9.57·ln(Cr) + 3.78·ln(Bili) + 11.20·ln(INR) + 6.43; MELD-Na adjusts for Na 125–137 mEq/L and plots three custom SVG graphs showing parameter sensitivity and component breakdowns.

Can I compare different reagent dilutions or lab scenarios side by side?

Yes. Use the "Compare (0/3)" button to pin up to 3 scenarios side by side.

Are entered values stored on any server?

No. Every calculation runs 100% locally in your browser.

Health & Fitness · Clinical Diagnostics & Scoring

MELD & MELD-Na Liver Disease Severity Score Reference Calculator: inputs, method, and how to read the result

Compute MELD(i) = 9.57·ln(Cr) + 3.78·ln(Bili) + 11.2·ln(INR) + 6.43 and Na adjustment.

Choose inputs for the case you are checking

The defaults are illustrative. Replace them with values for your case and keep the units shown beside each field.

  • Serum Creatinine Mg Dl: Serum Creatinine in mg/dL (clamped 1.0 to 4.0 per UNOS rule).
  • Total Bilirubin Mg Dl: Total Serum Bilirubin in mg/dL (minimum 1.0).
  • Inr Coagulation: International Normalized Ratio (INR, minimum 1.0).
  • Serum Sodium Meq L: Serum Sodium in mEq/L (clamped 125 to 137 mEq/L).

What the calculation includes

With the default values shown, MELD-Na Composite Score is 22 points. The calculation follows MELD-Na Liver Score Reference Equation; the formula and variable definitions above show how the inputs combine.

One-input check: With the other defaults held constant, changing Serum Creatinine Mg Dl from 1.4 mg/dL to 1.54 mg/dL changes MELD-Na Composite Score from 22 points to 23 points. This is a comparison inside the calculator's stated model, not a prediction.

Where to use caution

  • Uses standard IUPAC atomic weights, 25°C (298.15 K) reference thermodynamics, and published clinical literature equations.
  • Educational and laboratory reference tool only; clinical scoring calculators do not replace professional medical judgment or institutional protocols.

Scope: IUPAC / NIH Laboratory & Clinical Reference Standard Check the assumptions and limitations against your situation before relying on the estimate.

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