Cockcroft-Gault Creatinine Clearance (CrCl mL/min) Medication Dosing Calculator

Compute CrCl = [(140 − Age) × Weight_kg / (72 × SCr)] × SexFactor.

Estimated Creatinine Clearance (CrCl)
61.67 mL/min
Unadjusted Male Baseline CrCl 61.67 mL/min
Daily Filtered Volume Equivalent 88.8 L/day
Inverse Serum Creatinine (1/SCr) 0.77 dL/mg
Inputs
years
Patient age in years.
kg
Actual or ideal/adjusted body weight in kilograms.
mg/dL
Serum creatinine concentration in mg/dL.
factor
Sex factor (1.00 for biological male, 0.85 for biological female).
Results & Graph
Estimated Creatinine Clearance (CrCl)
61.67 mL/min
Unadjusted Male Baseline CrCl
61.67 mL/min
Daily Filtered Volume Equivalent
88.8 L/day
Inverse Serum Creatinine (1/SCr)
0.77 dL/mg

Estimated Creatinine Clearance (CrCl)

Graph 1 • Age Years Sensitivity Recalculates the domain equation across 50% to 150% of the primary input while holding other parameters constant.
0 mL/min 46.5 mL/min 93.1 mL/min 50%: 86.18 mL/min 86.2 50% 75%: 73.92 mL/min 73.9 75% 100%: 61.67 mL/min 61.7 100% 125%: 49.41 mL/min 49.4 125% 150%: 37.16 mL/min 37.2 150%
Graph 2 • Primary & Supporting Metric Comparison Compares the primary output alongside supporting domain benchmarks.
Estimated Creatinine Clearance (CrCl) 61.67 mL/min Unadjusted Male Baseline CrCl 61.67 mL/min Daily Filtered Volume Equivalent 88.8 L/day Inverse Serum Creatinine (1/SCr) 0.77 dL/mg
Graph 3 • Exact Output Table & Units Displays each calculated output in its exact domain unit.
Estimated Creatinine Clearance (CrCl)61.67 mL/minUnadjusted Male Baseline CrCl61.67 mL/minDaily Filtered Volume Equivalent88.8 L/dayInverse Serum Creatinine (1/SCr)0.77 dL/mg
Summary: Cockcroft-Gault Creatinine Clearance is 61.7 mL/min (for age 62, 74 kg, SCr 1.3 mg/dL, sex factor 1).
Summary: Cockcroft-Gault Creatinine Clearance is 61.7 mL/min (for age 62, 74 kg, SCr 1.3 mg/dL, sex factor 1).
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Interactive chart & math engine powered by CalculatorGraph

Formula & Mathematical Methodology: Cockcroft-Gault CrCl Reference Equation

CrClmL/min = [ ((140 − Age) × Weightkg) / (72 × SerumCrmg/dL) ] × SexMultiplier
CrCl_mL/min = [ ((140 − Age) × Weight_kg) / (72 × SerumCr_mg/dL) ] × SexMultiplier
  • ageYears: Age Years (years)
  • weightKg: Weight Kg (kg)
  • serumCreatinineMgDl: Serum Creatinine Mg Dl (mg/dL)
  • sexMultiplier: Sex Multiplier (factor)

Rounding: Laboratory and clinical equations retain full floating-point precision and round displayed results to 2 decimal places.

Worked Example: Reference Calculation: Cockcroft-Gault CrCl

Compute CrCl = [(140 − Age) × Weight_kg / (72 × SCr)] × SexFactor.

  1. Enter the reagent concentrations, assay readings, or clinical laboratory parameters.
  2. Compute the standard formula: CrCl_mL/min = [ ((140 − Age) × Weight_kg) / (72 × SerumCr_mg/dL) ] × SexMultiplier.
  3. Review the primary result, supporting reference intervals, and 3 SVG visualizations.
Result: Evaluates Cockcroft-Gault CrCl via CrCl_mL/min = [ ((140 − Age) × Weight_kg) / (72 × SerumCr_mg/dL) ] × SexMultiplier.

Frequently Asked Questions

What formula is used by the Cockcroft-Gault Creatinine Clearance (CrCl mL/min) Medication Dosing Calculator?

It computes CrCl_mL/min = [ ((140 − Age) × Weight_kg) / (72 × SerumCr_mg/dL) ] × SexMultiplier and plots three custom SVG graphs showing parameter sensitivity and component breakdowns.

Can I compare different reagent dilutions or lab scenarios side by side?

Yes. Use the "Compare (0/3)" button to pin up to 3 scenarios side by side.

Are entered values stored on any server?

No. Every calculation runs 100% locally in your browser.

Health & Fitness · Pharmacology & Critical Care

Cockcroft-Gault Creatinine Clearance (CrCl mL/min) Medication Dosing Calculator: inputs, method, and how to read the result

Compute CrCl = [(140 − Age) × Weight_kg / (72 × SCr)] × SexFactor.

Choose inputs for the case you are checking

The defaults are illustrative. Replace them with values for your case and keep the units shown beside each field.

  • Age Years: Patient age in years.
  • Weight Kg: Actual or ideal/adjusted body weight in kilograms.
  • Serum Creatinine Mg Dl: Serum creatinine concentration in mg/dL.
  • Sex Multiplier: Sex factor (1.00 for biological male, 0.85 for biological female).

What the calculation includes

With the default values shown, Estimated Creatinine Clearance (CrCl) is 61.67 mL/min. The calculation follows Cockcroft-Gault CrCl Reference Equation; the formula and variable definitions above show how the inputs combine.

One-input check: With the other defaults held constant, changing Age Years from 62 years to 68 years changes Estimated Creatinine Clearance (CrCl) from 61.67 mL/min to 56.92 mL/min. This is a comparison inside the calculator's stated model, not a prediction.

Where to use caution

  • Uses standard IUPAC atomic weights, 25°C (298.15 K) reference thermodynamics, and published clinical literature equations.
  • Educational and laboratory reference tool only; clinical scoring calculators do not replace professional medical judgment or institutional protocols.

Scope: IUPAC / NIH Laboratory & Clinical Reference Standard Check the assumptions and limitations against your situation before relying on the estimate.

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