Serum Anion Gap, Albumin-Corrected Anion Gap (Figge) & Delta Ratio Calculator

Compute standard Anion Gap, hypoalbuminemia correction, and Delta Ratio.

Albumin-Corrected Serum Anion Gap
24 mEq/L
Uncorrected Anion Gap 22 mEq/L
Delta Gap (Corrected AG − 12) 12 mEq/L
Delta Ratio (ΔAG / ΔHCO₃⁻) 1.5 ratio
Inputs
mEq/L
Serum Sodium [Na⁺] in mEq/L.
mEq/L
Serum Chloride [Cl⁻] in mEq/L.
mEq/L
Serum Bicarbonate [HCO₃⁻] in mEq/L.
g/dL
Serum Albumin in g/dL (normal reference 4.0 g/dL).
Results & Graph
Albumin-Corrected Serum Anion Gap
24 mEq/L
Uncorrected Anion Gap
22 mEq/L
Delta Gap (Corrected AG − 12)
12 mEq/L
Delta Ratio (ΔAG / ΔHCO₃⁻)
1.5 ratio

Albumin-Corrected Serum Anion Gap

Graph 1 • Serum Sodium Meq L Sensitivity Recalculates the domain equation across 50% to 150% of the primary input while holding other parameters constant.
-46 mEq/L 27.8 mEq/L 101.5 mEq/L 50%: -46 mEq/L -46 50% 75%: -11 mEq/L -11 75% 100%: 24 mEq/L 24 100% 125%: 59 mEq/L 59 125% 150%: 94 mEq/L 94 150%
Graph 2 • Primary & Supporting Metric Comparison Compares the primary output alongside supporting domain benchmarks.
Albumin-Corrected Serum Anion Gap 24 mEq/L Uncorrected Anion Gap 22 mEq/L Delta Gap (Corrected AG − 12) 12 mEq/L Delta Ratio (ΔAG / ΔHCO₃⁻) 1.5 ratio
Graph 3 • Exact Output Table & Units Displays each calculated output in its exact domain unit.
Albumin-Corrected Serum Anion Gap24 mEq/LUncorrected Anion Gap22 mEq/LDelta Gap (Corrected AG − 12)12 mEq/LDelta Ratio (ΔAG / ΔHCO₃⁻)1.5 ratio
Summary: Uncorrected Anion Gap is 22 mEq/L; adjusting for albumin 3.2 g/dL yields 24 mEq/L with a Delta Ratio of 1.5.
Summary: Uncorrected Anion Gap is 22 mEq/L; adjusting for albumin 3.2 g/dL yields 24 mEq/L with a Delta Ratio of 1.5.
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Formula & Mathematical Methodology: Anion Gap & Delta Ratio Reference Equation

AG = Na − (Cl + HCO₃)
CorrectedAG = AG + 2.5 × (4.0 − Albuming/dL)
DeltaRatio = CorrectedAG − 1224 − HCO₃
AG = Na − (Cl + HCO₃); Corrected_AG = AG + 2.5 × (4.0 − Albumin_g/dL); DeltaRatio = (Corrected_AG − 12) / (24 − HCO₃)
  • serumSodiumMeqL: Serum Sodium Meq L (mEq/L)
  • serumChlorideMeqL: Serum Chloride Meq L (mEq/L)
  • serumBicarbonateMeqL: Serum Bicarbonate Meq L (mEq/L)
  • serumAlbuminGdl: Serum Albumin Gdl (g/dL)

Rounding: Laboratory and clinical equations retain full floating-point precision and round displayed results to 2 decimal places.

Worked Example: Reference Calculation: Anion Gap & Delta Ratio

Compute standard Anion Gap, hypoalbuminemia correction, and Delta Ratio.

  1. Enter the reagent concentrations, assay readings, or clinical laboratory parameters.
  2. Compute the standard formula: AG = Na − (Cl + HCO₃); Corrected_AG = AG + 2.5 × (4.0 − Albumin_g/dL); DeltaRatio = (Corrected_AG − 12) / (24 − HCO₃).
  3. Review the primary result, supporting reference intervals, and 3 SVG visualizations.
Result: Evaluates Anion Gap & Delta Ratio via AG = Na − (Cl + HCO₃); Corrected_AG = AG + 2.5 × (4.0 − Albumin_g/dL); DeltaRatio = (Corrected_AG − 12) / (24 − HCO₃).

Frequently Asked Questions

What formula is used by the Serum Anion Gap, Albumin-Corrected Anion Gap (Figge) & Delta Ratio Calculator?

It computes AG = Na − (Cl + HCO₃); Corrected_AG = AG + 2.5 × (4.0 − Albumin_g/dL); DeltaRatio = (Corrected_AG − 12) / (24 − HCO₃) and plots three custom SVG graphs showing parameter sensitivity and component breakdowns.

Can I compare different reagent dilutions or lab scenarios side by side?

Yes. Use the "Compare (0/3)" button to pin up to 3 scenarios side by side.

Are entered values stored on any server?

No. Every calculation runs 100% locally in your browser.

Health & Fitness · Clinical Diagnostics & Scoring

Serum Anion Gap, Albumin-Corrected Anion Gap (Figge) & Delta Ratio Calculator: inputs, method, and how to read the result

Compute standard Anion Gap, hypoalbuminemia correction, and Delta Ratio.

Choose inputs for the case you are checking

The defaults are illustrative. Replace them with values for your case and keep the units shown beside each field.

  • Serum Sodium Meq L: Serum Sodium [Na⁺] in mEq/L.
  • Serum Chloride Meq L: Serum Chloride [Cl⁻] in mEq/L.
  • Serum Bicarbonate Meq L: Serum Bicarbonate [HCO₃⁻] in mEq/L.
  • Serum Albumin Gdl: Serum Albumin in g/dL (normal reference 4.0 g/dL).

What the calculation includes

With the default values shown, Albumin-Corrected Serum Anion Gap is 24 mEq/L. The calculation follows Anion Gap & Delta Ratio Reference Equation; the formula and variable definitions above show how the inputs combine.

One-input check: With the other defaults held constant, changing Serum Sodium Meq L from 140 mEq/L to 154 mEq/L changes Albumin-Corrected Serum Anion Gap from 24 mEq/L to 38 mEq/L. This is a comparison inside the calculator's stated model, not a prediction.

Where to use caution

  • Uses standard IUPAC atomic weights, 25°C (298.15 K) reference thermodynamics, and published clinical literature equations.
  • Educational and laboratory reference tool only; clinical scoring calculators do not replace professional medical judgment or institutional protocols.

Scope: IUPAC / NIH Laboratory & Clinical Reference Standard Check the assumptions and limitations against your situation before relying on the estimate.

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